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Medical Assistant in Charleston, SC

Comprehensive guide to medical assistant salaries in Charleston, SC. Charleston medical assistants earn $38,338 median. Compare to national average, see take-home pay, top employers, and best neighborhoods.

Median Salary

$38,338

Above National Avg

Hourly Wage

$18.43

Dollars / Hr

Workforce

0.3k

Total Jobs

Growth

+15%

10-Year Outlook

A Career Analyst's Guide for Medical Assistants in Charleston, South Carolina

So, you're thinking about making a move to Charleston as a Medical Assistant. Good choice. This isn't just a historic city with cobblestone streets; it's a growing healthcare hub with a distinct character and real economic demands. As a local career analyst, I'm not here to sell you on the charm—I'm here to give you the hard numbers, the neighborhood breakdowns, and the insider knowledge you need to make a smart decision. Let's break down what it really looks like to live and work here.

The Salary Picture: Where Charleston Stands

First, let's talk money. The data paints a clear, if slightly sobering, picture for Medical Assistants in the Charleston-North Charleston metro area. According to the U.S. Bureau of Labor Statistics (BLS), the median salary for Medical Assistants here is $38,338 per year, which breaks down to an hourly rate of $18.43. This is just a hair above the national average of $38,270, but it's crucial to understand that this "median" number is pulled down by a high concentration of entry-level roles in busy, high-volume practices.

Where you fall on the spectrum depends heavily on your experience, specialty, and the type of employer. Here’s a realistic breakdown:

Experience Level Estimated Annual Salary Range Key Influencing Factors in Charleston
Entry-Level (0-2 years) $32,000 - $36,000 Large hospital systems (MUSC, Roper), urgent care chains, and smaller private practices. This is your starting point.
Mid-Level (2-5 years) $37,000 - $42,000 Specialized clinics (cardiology, orthopedics), experience with specific EMR systems, or roles with more administrative duties.
Senior/Lead MA (5-10 years) $42,000 - $48,000 Often found in private specialty groups or taking on lead/managerial roles within a practice. May include lead MA responsibilities.
Expert/Specialized (10+ years) $48,000+ Highly specialized roles (e.g., surgical assisting, research coordination at MUSC), or transitioning into practice management.

How does Charleston compare to other SC cities? It consistently ranks in the middle of the pack. It pays better than rural areas but falls short of the state's highest-paying metros. For instance, Columbia (home to the state's largest hospital system) often edges out Charleston slightly due to state government and university roles. Greenville, with its booming manufacturing and healthcare sector, also tends to have a slightly higher cost-adjusted salary for MAs. The BLS data for Metro Charleston shows there are 311 jobs in the field, with a 10-year job growth projection of 15%—strong growth, fueled by an aging population and the expansion of healthcare services.

Insider Tip: Don't just look at the base salary. A huge factor here is benefits, especially health insurance. The large hospital systems (MUSC, Roper) offer comprehensive packages that can offset a lower base pay compared to a smaller private practice that might pay a bit more in cash but with spotty benefits. Always calculate total compensation.

📊 Compensation Analysis

Charleston $38,338
National Average $38,270

📈 Earning Potential

Entry Level $28,754 - $34,504
Mid Level $34,504 - $42,172
Senior Level $42,172 - $51,756
Expert Level $51,756 - $61,341

Wage War Room

Real purchasing power breakdown

Select a city above to see who really wins the salary war.

The Real Take-Home: After Taxes and Rent

Let's get brutally honest about the math. A median salary of $38,338 is not a luxury income in Charleston. To understand your real purchasing power, we need to factor in taxes and the city's housing costs.

The average 1-bedroom apartment in the Charleston metro area rents for $1,424 per month. The city's Cost of Living Index is 100.6, meaning it's 0.6% more expensive than the national average. While not extreme, the housing market is the primary driver of that cost.

Here’s a monthly budget breakdown for a Medical Assistant earning the median salary:

Monthly Take-Home Pay (Est. after taxes): ~$2,550
Monthly Budget Breakdown:

  • Housing (1BR Avg. Rent): $1,424
  • Utilities (Electric, Water, Internet): $180
  • Groceries: $350
  • Transportation (Gas, Insurance, Car Payment): $350
  • Health Insurance (if not fully covered by employer): $150 (estimate)
  • Miscellaneous/Personal: $96

Monthly Surplus: ~ $0

This is a tight budget with almost no room for error. The calculation above assumes a modest car payment and no student loans. If you have significant debt or a more expensive car, you'll be in the red. Shared housing (a roommate) is extremely common for single MAs earning at the median, especially those looking to live in more desirable or convenient neighborhoods.

Can they afford to buy a home? On a median MA salary, buying a home in Charleston proper is very challenging. The median home price in the Charleston area is well over $450,000. To comfortably afford a starter home in this market, you'd typically need a household income of at least $80,000-$100,000. This makes dual-income households or advancing into a senior/lead role a near-necessity for homeownership within a reasonable commute.

💰 Monthly Budget

$2,492
net/mo
Rent/Housing
$872
Groceries
$374
Transport
$299
Utilities
$199
Savings/Misc
$748

📋 Snapshot

$38,338
Median
$18.43/hr
Hourly
311
Jobs
+15%
Growth

Where the Jobs Are: Charleston's Major Employers

Charleston's healthcare scene is dominated by a few key players, with growth spilling into the suburbs and surrounding counties.

  1. Medical University of South Carolina (MUSC) Health: The 800-pound gorilla. MUSC is the state's only comprehensive academic medical center. They hire MAs for their downtown campus, numerous outpatient clinics (like the MUSC Health Ashley River Tower), and their growing network of community hospitals in West Ashley, Summerville, and beyond. Hiring Trend: Massive expansion. They are aggressively hiring for their new facilities and to support their integrated health system. Experience with complex EMR systems (like Epic, which MUSC uses) is a huge plus.

  2. Roper St. Francis Healthcare: The other major hospital system, with three hospitals in the area (Roper, Bon Secours St. Francis, and Roper Northwoods). They have a strong presence in downtown Charleston and the West Ashley corridor. They are known for a more community-focused, "Southern hospitality" culture. Hiring Trend: Steady hiring, with a focus on outpatient clinics and surgical centers. They tend to be very stable employers.

  3. Trident Health (HCA Healthcare): Located in Summerville and Charleston, this system includes Trident Medical Center and Summerville Medical Center. It serves the growing suburbs and is a major employer in the Dorchester County area. Hiring Trend: Consistent, driven by suburban population growth. Often a good fit for MAs who prefer a less academic, more fast-paced community hospital environment.

  4. Charleston ENT & Allergy: A large, well-established private specialty group. Working here often means diving deep into otolaryngology (ENT) or allergy procedures, which can be more technical and rewarding. Hiring Trend: Stable. They are a pillar of the local community, and turnover is often low, meaning openings are less frequent but highly competitive.

  5. Southeastern Medical Specialists (SMS): A large multi-specialty private practice with locations in West Ashley, Mount Pleasant, and Summerville. They cover a wide range of specialties (cardiology, gastroenterology, endocrinology). Hiring Trend: Growing. They are a prime example of the private practice consolidation trend and are often hiring to support their expanding service lines.

Insider Tip: Don't overlook urgent care chains (like AFC Urgent Care or MedExpress) and large primary care groups (like Palmetto Primary Care Physicians). They have high turnover and constant openings, making them excellent places to get your foot in the door and gain experience.

Getting Licensed in SC

South Carolina has a straightforward but mandatory process for Medical Assistants, which protects the title and scope of practice.

  • The Requirement: You must be a graduate of an accredited Medical Assistant program (by CAAHEP or ABHES) and pass a national certification exam.
  • Accepted Certifications: The most common are the Certified Medical Assistant (CMA) from the AAMA or the Registered Medical Assistant (RMA) from the AMT. The National Healthcareer Association's Certified Clinical Medical Assistant (CCMA) is also widely accepted.
  • Cost: Exam fees range from $120 to $250, depending on the certifying body. State licensure itself is not separate; your certification is your license to practice.
  • Timeline to Get Started: If you are not yet certified, you'll need to complete an accredited program (typically 1-2 years) and then study for/take your exam. If you are already certified from another state, you can apply for jobs immediately—just ensure your certification is current and will be recognized by South Carolina employers (which all major ones do). You must also register with the South Carolina Department of Labor, Licensing and Regulation (LLR) through their online portal, which is a simple formality.

Insider Tip: Always verify with the employer. Some practices, especially smaller ones, might be less familiar with out-of-state certifications. Having your certification card and proof of program completion ready is key.

Best Neighborhoods for Medical Assistants

Your commute and lifestyle will be dictated by where you live. Here’s a neighborhood breakdown focused on proximity to major employers and affordability.

Neighborhood Avg. 1BR Rent Vibe & Commute Best For...
West Ashley $1,250 - $1,400 Suburban, family-friendly. 10-15 min to MUSC/Roper via the Crosstown. More house for your money. MAs working at MUSC's main campus, Roper St. Francis, or Trident Health.
North Charleston (Park Circle area) $1,100 - $1,300 Industrial-turned-artsy. 15-20 min to downtown hospitals. Trendy, diverse, and more affordable. Those seeking a vibrant, less expensive community with a short commute.
Summerville $1,150 - $1,350 Classic suburb 25-35 mins from downtown. Family-centric, good schools, and lower cost of living. MAs working at Trident Health in Summerville or those who prioritize space and schools.
Mount Pleasant $1,600+ Upscale, coastal, and family-oriented. 20-30 min commute (can be longer via I-526). Very desirable but pricey. MAs with a higher household income or those working at the Roper Mount Pleasant campus.
Downtown / Harleston Village $1,800+ Historic, walkable, premium. 5-15 min walk/bike to MUSC/Roper. Very expensive for a single MA on a median salary. High-earning MAs (senior/lead) or those in a dual-income household.

Insider Tip: Traffic in Charleston is notoriously bad. The I-26/I-526 interchange is a daily bottleneck. Living close to your workplace, even if it's in a less "hip" neighborhood, can save you hours of frustration and gas money each week.

The Long Game: Career Growth

What does the future hold? The 10-year job growth of 15% is promising, but advancement requires strategy.

  • Specialty Premiums: The biggest salary jumps come from specializing. MAs in ophthalmology, cardiology, or surgical assisting often command higher pay due to their advanced skill sets. Gaining experience with ophthalmic tech (like visual fields, OCTs) or cardiac device monitoring can open doors.
  • Advancement Paths:
    1. Lead MA / Office Manager: Supervising other MAs and handling administrative tasks (billing, scheduling, ordering). This is a natural progression for experienced MAs.
    2. Clinical Research Coordinator: Charleston has a robust research scene, especially at MUSC. MAs with strong organizational skills can transition into this higher-paying, detail-oriented field.
    3. Healthcare Administration: Pursuing a degree in healthcare management can move you out of direct patient care and into management roles, with significantly higher earning potential.
  • 10-Year Outlook: The demand will remain strong. However, the role will continue to evolve. Proficiency with telehealth platforms, population health data, and patient outreach will become increasingly valuable. The MA who can blend clinical skills with tech-savviness and communication will have the most staying power.

The Verdict: Is Charleston Right for You?

This is a city of trade-offs. It offers unparalleled quality of life, but it demands a tight budget and a strategic career approach.

Pros Cons
Strong Job Market with 15% growth and diverse employers. High Cost of Living, primarily driven by housing.
Excellent Work/Life Balance outside of rush hour; beautiful beaches and nature nearby. Median Salary ($38,338) is tight for a single person to live alone comfortably.
Rich Culture & History—you're living in a postcard. Traffic congestion can be a major daily stressor.
Path to Specialization in cardiology, ENT, research, etc. Can be challenging to buy a home on a single MA's income.
Slower, Southern Pace compared to major metros like Atlanta. Humidity and Hurricane Season (June-Nov) are real factors.

Final Recommendation:

Charleston is an excellent choice for Medical Assistants who are willing to start in shared housing, prioritize their career growth, and embrace the local lifestyle. It's ideal for those who value a strong community, outdoor activities, and a unique cultural scene over a high disposable income.

It's a tougher choice for those with high debt, a desire for immediate homeownership on a single income, or an aversion to heat and humidity. If you're coming from a higher-cost city, you may find the salary/lifestyle balance manageable, but if you're from a low-cost rural area, the financial shock will be real.

Do your homework: secure a job offer before you move, budget carefully, and be prepared for the upfront costs of a security deposit and first month's rent.

FAQs

Q1: I'm moving from out of state. Do I need to re-certify?
No. South Carolina recognizes national certifications from AAMA, AMT, NHA, etc. As long as your certification is current, you can work. You should register with the SC LLR as a formality, but it's not a barrier to employment.

Q2: What's the best way to find a Medical Assistant job in Charleston?
Start with the big systems: check the MUSC Health, Roper St. Francis, and Trident Health career pages directly. Use LinkedIn and Indeed, but also look at local healthcare-specific job boards. Networking through professional associations like the South Carolina Society of Medical Assistants can be very effective.

Q3: Is it possible to live in Charleston on the median salary?
Yes, but it requires a budgeting mindset. You will almost certainly need a roommate or to live in the more affordable suburbs like North Charleston or West Ashley. Avoiding a car payment by using public transit or biking can also free up significant funds.

Q4: Are there opportunities for part-time or flexible schedules?
Yes, especially in private practices and urgent care centers. Larger hospital systems are more likely to offer full-time positions with benefits. Part-time roles are common but often come without health insurance, which is a major consideration on a lower salary.

Q5: What's the biggest mistake new MAs make when moving to Charleston?
Underestimating the cost of living and the commute. People get seduced by the charm of a downtown apartment but can't afford it on their salary, leading to financial stress. Or, they pick a cheap place in the suburbs without considering the brutal commute to the hospital districts. Always budget for the total cost of living and visit the area to test the commute if possible.

Sources: U.S. Bureau of Labor Statistics (BLS) Occupational Employment and Wage Statistics, Zillow Rental Market Data, U.S. Census Bureau, South Carolina Department of Labor, Licensing and Regulation (LLR).

Explore More in Charleston

Dive deeper into the local economy and lifestyle.

Data Sources: Bureau of Labor Statistics (OEWS May 2024), SC State Board, Bureau of Economic Analysis (RPP 2024), Redfin Market Data
Last updated: January 28, 2026 | Data refresh frequency: Monthly