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Registered Nurse in Columbia, SC

Comprehensive guide to registered nurse salaries in Columbia, SC. Columbia registered nurses earn $84,236 median. Compare to national average, see take-home pay, top employers, and best neighborhoods.

Median Salary

$84,236

Vs National Avg

Hourly Wage

$40.5

Dollars / Hr

Workforce

1.3k

Total Jobs

Growth

+6%

10-Year Outlook

The Salary Picture: Where Columbia Stands

Let's get straight to the numbers. In Columbia, the median salary for a Registered Nurse is $84,236/year, which breaks down to an hourly rate of $40.5/hour. This puts you in a competitive position, especially when you consider the local cost of living. Nationally, the average RN salary is $86,070/year, so Columbia is just a hair below the U.S. average. However, the financial picture changes dramatically when you factor in the city's affordability.

For context, there are approximately 1,278 nursing jobs in the metro area, and the 10-year job growth is projected at 6%. This isn't a booming, explosive market, but it's stable, consistent, and offers plenty of opportunities for those already in the area or looking to relocate.

Hereโ€™s how salaries typically break down by experience level in the Columbia area. These are realistic estimates based on local employer pay scales and collective bargaining agreements at major hospitals.

Experience Level Annual Salary Estimate Hourly Rate Estimate Typical Roles
Entry-Level (0-2 yrs) $68,000 - $75,000 $32.50 - $36.00 Med-Surg, Telemetry, Orthopedics
Mid-Level (3-7 yrs) $80,000 - $95,000 $38.50 - $45.70 ICU, ER, L&D, Clinical Nurse Educator
Senior (8-15 yrs) $92,000 - $110,000 $44.20 - $52.80 Charge Nurse, Supervisor, Specialty Clinic Manager
Expert/Leadership (15+ yrs) $105,000 - $135,000+ $50.50 - $64.90+ Nurse Manager, Director, APRN (NP/CRNA)

Insider Tip: The jump from mid-level to senior often comes with a move into a charge nurse or preceptor role. Getting your BSN is almost a prerequisite for moving into management-track positions at Palmetto Health or Prisma Health. Certifications in a specialty (like CCRN for critical care or OCN for oncology) can add $3,000-$8,000 annually in some local employers.

When you compare Columbia to other major cities in South Carolina, the salary difference isn't huge, but the lifestyle trade-off is significant.

City Median RN Salary 1BR Avg Rent Cost of Living Index (US Avg=100)
Columbia $84,236 $1,110 92.9
Charleston $87,500 $1,650 112.0
Greenville $83,500 $1,280 98.5
Myrtle Beach $78,000 $1,350 95.0

While Charleston pays slightly more, the rent is nearly 50% higher and the cost of living is 19% above the national average. In Columbia, your $84,236 goes much further, offering a more manageable lifestyle for single professionals or young families.

๐Ÿ“Š Compensation Analysis

Columbia $84,236
National Average $86,070

๐Ÿ“ˆ Earning Potential

Entry Level $63,177 - $75,812
Mid Level $75,812 - $92,660
Senior Level $92,660 - $113,719
Expert Level $113,719 - $134,778

Wage War Room

Real purchasing power breakdown

Select a city above to see who really wins the salary war.

The Real Take-Home: After Taxes and Rent

Let's run a realistic monthly budget for a single RN earning the Columbia median of $84,236. We'll use a 2023 tax estimate (federal, state, and FICA) of approximately 28% for a single filer with the standard deduction. This is a conservative estimate; your take-home could be slightly higher with pre-tax deductions for health insurance or a 401(k).

  • Annual Salary: $84,236
  • Estimated Monthly Gross: $7,020
  • Est. Monthly Taxes & Deductions (28%): ~$1,965
  • Estimated Monthly Take-Home Pay: $5,055

Now, let's budget for a typical Registered Nurse in Columbia. We'll assume a 1BR apartment average rent of $1,110/month.

Monthly Budget Breakdown:

  • Rent: $1,110
  • Utilities (Electric, Water, Internet, Phone): $350
  • Car Payment & Insurance: $550 (Columbia is car-dependent)
  • Groceries & Household: $400
  • Health Insurance (pre-tax): $250 (varies by employer)
  • Student Loans: $300 (national average)
  • Retirement (401k 5%): $350
  • Personal & Entertainment: $700
  • Total Monthly Expenses: $4,010

Monthly Surplus: $1,045

This surplus is healthy. It allows for savings, emergency funds, or discretionary spending. The key affordability factor is the rent. If you choose a nicer apartment in The Vista or Cayce, your rent might climb to $1,400, reducing your surplus but still keeping you comfortably in the green.

Can they afford to buy a home?
Yes, absolutely. The median home price in the Columbia metro is approximately $250,000 - $285,000. With a $1,045 monthly surplus, a 20-year mortgage on a $260,000 home (assuming a 6.5% interest rate and 10% down) would be around $1,550/month (including taxes and insurance). This is manageable on a single RN's salary, especially if you have a two-income household or work occasional overtime. Many RNs in Columbia live in suburbs like Northeast Columbia (Blythewood area), Irmo, or Cayce, where single-family homes are prevalent and the commute to the major hospitals is reasonable.

๐Ÿ’ฐ Monthly Budget

$5,475
net/mo
Rent/Housing
$1,916
Groceries
$821
Transport
$657
Utilities
$438
Savings/Misc
$1,643

๐Ÿ“‹ Snapshot

$84,236
Median
$40.5/hr
Hourly
1,278
Jobs
+6%
Growth

Where the Jobs Are: Columbia's Major Employers

Columbia's healthcare landscape is dominated by two massive systems, but there are also significant opportunities in public health, state government, and specialty clinics. The 1,278 jobs in the metro are concentrated here.

  1. Prisma Health Midlands (formerly Palmetto Health): This is the state's largest non-profit healthcare provider. They operate Prisma Health Richland Hospital (downtown, near the University of South Carolina campus) and Prisma Health Baptist (northeast). They are in a perpetual state of growth and renovation. Hiring is constant, especially for Med-Surg, ICU, and ER. Their nurse residency program is one of the most established in the state. Insider Tip: Prisma often has internal job boards with positions that don't appear on public sites. If you're a current employee, you can often transfer units easier than an external hire can get in.

  2. Lexington Medical Center: Located in West Columbia, just across the river, this is a thriving community hospital that feels more like a family. Itโ€™s a major employer for nurses in the western suburbs and has a strong reputation for oncology and cardiac care. Their growth has been explosive, with a massive new patient tower completed in recent years. Insider Tip: LMC is known for a slightly more "Southern" and personal culture compared to the massive Prisma system. It's a great fit if you prefer a slightly smaller, community-focused environment.

  3. Dorn VA Medical Center: Located in the VA hospital district, this is a major federal employer. VA nursing is a distinct career path with excellent benefits, federal holidays off, and a focus on veteran care. The patient population is unique (geriatric, chronic conditions, PTSD). Hiring can be slower due to the federal application process, but turnover is lower once you're in. Insider Tip: For VA jobs, patience with the USAJobs.gov process is required. It can take 2-4 months from application to start date.

  4. South Carolina Department of Health and Environmental Control (DHEC): The state public health agency has its headquarters in Columbia. They hire RNs for public health clinics, school health programs, and epidemiological roles. These are Monday-Friday, government jobs with great benefits and retirement. They are less clinical and more community-focused. Insider Tip: These positions are posted on the state careers website and are highly competitive for the stability they offer.

  5. MUSC Health (Medical University of South Carolina): While its main campus is in Charleston, MUSC has a growing presence in Columbia, primarily through its behavioral health services and outpatient clinics. They are expanding their footprint, offering roles in psychiatry, addiction medicine, and specialty outpatient care. Insider Tip: MUSC often brings a different, research-oriented culture to the Columbia market. It's a good option for RNs interested in cutting-edge treatments and academic medicine.

  6. Columbia Regional Hospital (CRH): Part of the national HCA Healthcare chain, CRH is another key player, especially in surgical services and orthopedics. It provides an alternative to the non-profit giants and often has different internal policies and union dynamics. Insider Tip: HCA hospitals can be more driven by metrics and throughput. If you thrive in a fast-paced, efficiency-focused environment, CRH is worth a look.

Getting Licensed in SC

If you're coming from another state, the process is straightforward but requires planning. The South Carolina Board of Nursing (SCBON) is the governing body.

1. If you are already an RN with a compact license (e.g., from NC, TN, GA, FL):
You're in luck. South Carolina is a member of the Nurse Licensure Compact (NLC). If your primary state of residence is in a compact state, you can practice in SC with your existing license. You do not need to apply for a separate SC license. Verify your state's compact status on the NLC website.

2. If you are a nurse from a non-compact state:
You'll need to apply for licensure by endorsement.

Steps & Costs (as of 2023-2024):

  • Application Fee: $100 (non-refundable)
  • Background Check: $45 (through the SCBON's approved vendor)
  • Proof of Licensure: Send verification from your original state's board.
  • Education: Official transcript sent directly from your nursing school.
  • NCLEX: You must have passed the NCLEX-RN in your original state. No need to retake it.
  • Timeline: The process can take 4-8 weeks after submitting a complete application. Plan accordingly.

For New Graduates (NCLEX Exam):
If you are a new graduate from a non-compact state, you must apply for an SC license by examination. The fees are similar. You must pass the NCLEX-RN to be licensed. The average time from application to authorization to test (ATT) is 2-4 weeks, then you schedule the exam.

Insider Tip: The SCBON website is your best friend. Keep a digital file of all your documents (transcripts, certificates, old license) ready for upload. The most common delay is missing or incomplete paperwork.

Best Neighborhoods for Registered Nurses

Where you live in Columbia greatly impacts your commute and lifestyle. The city is spread out, and traffic on I-26 and I-77 can be heavy during rush hour (7-8:30 AM and 4:30-6 PM).

For the Urban Professional (Walkability & Nightlife):

  • The Vista & Main Street: This is the downtown core, filled with restaurants, bars, and boutiques. You're a short walk from Prisma Health Richland. It's ideal for the single RN who wants to be in the center of the action.
  • 1BR Rent: $1,300 - $1,800
  • Commute: 5-10 minute drive or walk to Prisma Richland. 15-20 minutes to Lexington Medical (depending on traffic).

For the Quiet & Family-Oriented (West of the River):

  • Cayce & West Columbia: These suburbs offer more space, single-family homes, and a quieter pace. They're home to many young families and first-time homebuyers. The drive to Lexington Medical Center is very easy.
  • 1BR Rent: $1,000 - $1,250
  • Commute: 10-15 minutes to Lexington Medical or Prisma Baptist. 20-25 minutes to Prisma Richland (crossing the Gervais St. Bridge).

For the Budget-Conscious & Convenience:

  • Northeast Columbia (Blythewood area): This area is growing rapidly, with new apartment complexes and subdivisions. It's close to I-77, providing a direct route to Prisma Baptist and the VA. It's less expensive and less congested than downtown.
  • 1BR Rent: $950 - $1,200
  • Commute: 10-15 minutes to Prisma Baptist/VA. 20-25 minutes to Prisma Richland.

Insider Tip: If you work night shift, your commute is irrelevantโ€”you're driving against traffic. This is a huge perk. Many night-shift RNs live farther out for cheaper rent since their driving time is minimal. If you're on a rotating shift, stick to a central location like Cayce or the North Main area.

The Long Game: Career Growth

Columbia is not an "up-or-out" city for nurses. It's a place where you can build a long, stable, and rewarding career without needing to constantly job-hop.

Specialty Premiums:
Specializations command a premium, but not as much as in major coastal metros. Expect a $2,000-$6,000 annual bump for certifications in:

  • Critical Care (CCRN): ICU, CVICU
  • Emergency (CEN): ER
  • Oncology (OCN): Lexington Medical has a strong program.
  • Labor & Delivery (RNC-OB): Always in high demand.

Advancement Paths:
The most common ladder is:

  1. Staff Nurse -> Charge Nurse (requires strong interpersonal skills and experience; small pay bump, often $3,000-$5,000).
  2. Charge Nurse -> Nurse Manager (requires a BSN, often an MSN, and leadership training; significant pay increase to $95,000-$115,000).
  3. Alternative Paths: Clinical Nurse Educator, Infection Preventionist, or Case Manager. These roles are often Monday-Friday and offer a break from direct patient care. They are highly competitive.

10-Year Outlook:
The 6% job growth is modest but meaningful. It means steady demand, not a hiring frenzy. The aging population in South Carolina will continue to drive demand for nurses in geriatrics, home health, and long-term care. Columbia's status as the state capital and home to major universities ensures a stable, non-cyclical job market. A nurse with 10 years of experience in Columbia will be highly valued and can easily command a salary in the $100,000+ range, especially if they move into a leadership or advanced practice role.

The Verdict: Is Columbia Right for You?

Pros Cons
Affordability: Your $84,236 salary stretches far. Homeownership is a realistic goal. Traffic & Sprawl: You need a car. Commutes can be long if you live far from your hospital.
Job Stability: Two major health systems (Prisma, LMC) and the VA provide a diverse, stable job market. Limited "Prestige": It's not a medical hub like Houston or Boston. Fewer cutting-edge research trials.
Southern Charm & Pace: Columbia has a relaxed, friendly vibe without the tourist crush of Charleston. Summers are Brutally Hot: From June to September, the humidity is extreme.
Central Location: Easy weekend trips to the mountains (4 hrs) or the coast (2 hrs). City Services: Some areas have older infrastructure. Public transit is virtually non-existent.
Strong Community Feel: The nursing community here is tight-knit. You'll see the same faces for years. Limited Cultural Diversity: Compared to larger cities, the cultural and culinary scene is growing but still developing.

Final Recommendation:
Columbia is an excellent choice for nurses who prioritize financial stability and quality of life over high-cost coastal living. It's ideal for:

  • New graduates looking for a low-cost place to start their career with strong hospital systems.
  • Mid-career nurses who want to buy a home and build a family without being house-poor.
  • Travel nurses seeking a stable, affordable base between contracts.

It may be less ideal for those seeking a high-energy, fast-paced urban lifestyle or those who want to be at the forefront of the most cutting-edge medical research. For the vast majority of RNs, Columbia offers a compelling, balanced package.

FAQs

1. I'm a new grad. Is it hard to get a job in Columbia?
Not particularly, but it's competitive for the top residency programs. Apply early (before graduation) and be flexible with your unit choice. Med-Surg is the easiest entry point. Having a BSN will give you a significant advantage over an ADN.

2. How does the cost of living compare to Charleston?
While your salary might be $3,000-$5,000 less in Columbia

Data Sources: Bureau of Labor Statistics (OEWS May 2024), SC State Board, Bureau of Economic Analysis (RPP 2024), Redfin Market Data
Last updated: January 27, 2026 | Data refresh frequency: Monthly