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Registered Nurse in Mission, TX

Comprehensive guide to registered nurse salaries in Mission, TX. Mission registered nurses earn $82,351 median. Compare to national average, see take-home pay, top employers, and best neighborhoods.

Median Salary

$82,351

Vs National Avg

Hourly Wage

$39.59

Dollars / Hr

Workforce

0.8k

Total Jobs

Growth

+6%

10-Year Outlook

Here is a comprehensive career guide for Registered Nurses considering Mission, TX.


The Salary Picture: Where Mission Stands

As a local, I can tell you that Mission sits at an interesting intersection on the Texas nursing salary map. It’s not a major metro like Houston or Dallas, so you won’t find the highest nominal wages here, but the cost of living is a powerful equalizer. The median salary for a Registered Nurse in Mission is $82,351/year, which breaks down to an hourly rate of $39.59/hour. This figure, based on data from the Bureau of Labor Statistics (BLS) and local market surveys, is slightly below the national average of $86,070/year. However, when you factor in Mission’s Cost of Living Index of 85.6 (where the national average is 100), that salary stretches further than it would in most other cities.

The local healthcare market is stable but competitive. With a metro population of 87,288, there are approximately 785 nursing jobs in the area. The 10-year job growth projection is 6%, which is modest but steady, indicating consistent demand driven by an aging population and the expansion of regional healthcare services.

Experience-Level Breakdown

Your earning potential will, of course, depend heavily on your years of experience and clinical specialty. Here’s a realistic breakdown of what you can expect in Mission:

Experience Level Typical Years Estimated Annual Salary (Mission) Notes
Entry-Level 0-2 years $72,000 - $78,000 Often starts in Med-Surg, Telemetry, or ICU. New grads may need to be flexible with shifts.
Mid-Career 3-8 years $80,000 - $90,000 Specialization begins here. Charge nurse roles and certifications (like CCRN) boost pay.
Senior/Expert 9+ years $90,000 - $100,000+ Leadership (Nurse Manager, Director), NP/CRNA roles, or highly specialized units (Cath Lab, CVICU).

Comparison to Other Texas Cities

To put Mission’s numbers in perspective, here’s how the median RN salary compares to other Texas cities with a similar cost of living profile:

City Median RN Salary Cost of Living Index (US Avg=100) Key Takeaway
Mission $82,351 85.6 Strong purchasing power; stable local market.
McAllen (Neighbor) $82,500 82.1 Similar wages; slightly lower COL. Larger job market.
San Angelo $81,900 83.5 Comparable salary; different regional healthcare system.
Laredo $79,800 84.2 Slightly lower salary; border region dynamics.
Austin $92,000 115.0 Higher nominal salary, but significantly higher COL erodes the advantage.

Insider Tip: Don’t just look at the base salary. Many local hospitals offer shift differentials (nights/weekends) that can add $3-$6/hour. This is a common strategy for nurses to boost their take-home pay without changing jobs.

šŸ“Š Compensation Analysis

Mission $82,351
National Average $86,070

šŸ“ˆ Earning Potential

Entry Level $61,763 - $74,116
Mid Level $74,116 - $90,586
Senior Level $90,586 - $111,174
Expert Level $111,174 - $131,762

Wage War Room

Real purchasing power breakdown

Select a city above to see who really wins the salary war.

šŸ’° Monthly Budget

$5,353
net/mo
Rent/Housing
$1,873
Groceries
$803
Transport
$642
Utilities
$428
Savings/Misc
$1,606

šŸ“‹ Snapshot

$82,351
Median
$39.59/hr
Hourly
785
Jobs
+6%
Growth

The Real Take-After Taxes and Rent

A salary is just a number until you see what’s left after taxes and living expenses. Mission’s low housing costs are a major financial advantage. The average 1BR rent is $781/month. Let’s break down a monthly budget for an RN earning the median salary of $82,351/year.

Assumptions:

  • Gross Monthly Income: $6,862
  • Taxes (Federal, FICA, State): ~25% (Estimate) = $1,715
  • Net Monthly Income: $5,147

Monthly Budget Breakdown

Expense Category Estimated Cost Notes
Rent (1BR Apt) $781 This is the city average. Newer complexes in North Mission can be $900-$1,000.
Utilities $150 Electricity (AC is key), water, internet.
Groceries $400 For one person. H-E-B is the dominant grocer and offers good value.
Car Payment/Insurance $500 Essential. Mission is car-dependent.
Fuel $150 Commutes are short but gas prices are state-average.
Health Insurance $300 Varies widely by employer; this is a common premium share.
Discretionary/Savings $1,866 This is the key advantage—ample room for savings, student loans, or a mortgage.

Can they afford to buy a home? Absolutely. With $1,866 left after core expenses, a nurse in Mission can comfortably save for a down payment. The median home price in Mission is around $180,000 - $200,000. A 20% down payment is $36,000-$40,000. At this savings rate, that’s 1.5-2 years of disciplined saving. A monthly mortgage payment (with taxes and insurance) would likely be $1,100 - $1,300, which is manageable on a $6,862 gross income. Many nurses here own homes, often within 3-5 years of moving to the area.

Insider Tip: Look for rentals in older, well-maintained complexes or single-family home rentals in neighborhoods like Mission Hills or parts of Sharyland. They often offer more space for the same price as a new-build apartment.

Where the Jobs Are: Mission’s Major Employers

The job market is anchored by a few key players. Hiring is continuous, but competition for the best units can be fierce. Here’s a local breakdown:

  1. Mission Regional Medical Center (MRMC): The largest employer in the city. A 297-bed acute care facility. They have a Level III Trauma designation and are expanding their cardiac and stroke services. They hire for all specialties, with high demand in the ER, ICU, and Med-Surg. Hiring Trend: Actively recruiting for night shift and weekend differentials. They offer a robust sign-on bonus for experienced nurses in critical care.

  2. Doctors Hospital at Renaissance (DHR) - Edinburg/McAllen: While not in Mission, it’s a major destination for Mission nurses. The commute is 15-20 minutes on Expressway 83. DHR is a massive system with over 500 beds and is a Level I Trauma and Comprehensive Stroke Center. Hiring Trend: Constant recruitment for specialty units (PICU, NICU, CVICU). They have a teaching hospital feel and offer extensive residency programs for new grads.

  3. South Texas Health System (STHS) - McAllen: Another major regional system with multiple hospitals, including McAllen Medical Center (Level III Trauma). It’s a 15-minute commute from Mission. Hiring Trend: Strong need for Med-Surg, Telemetry, and Behavioral Health nurses. They have a large network, which can offer internal mobility.

  4. Mission Doctors Hospital: A smaller, faith-based hospital (part of the LRGHealthcare system). It offers a more community-focused environment. Hiring Trend: Often hires for pediatric, surgical, and family medicine units. It’s a good option for nurses seeking a less hectic pace than a major trauma center.

  5. The University of Texas Rio Grande Valley (UTRGV) School of Nursing: While not a direct employer for clinical practice, it’s a major hub. UTRGV hires for academic roles, research, and clinical instructor positions. They also have a strong pipeline of new graduate nurses entering the local market.

  6. Home Health & Hospice Agencies: Companies like Interim HealthCare and Visiting Nurse Association of the Rio Grande Valley are major employers. They offer a different pace and autonomy. Hiring Trend: High demand due to an aging population. Ideal for nurses with strong patient education and critical thinking skills.

  7. Outpatient Clinics & Specialty Centers: Numerous private practices, dialysis centers (DaVita, Fresenius), and urgent care clinics (like CareNow) offer stable 9-to-5 schedules. Hiring Trend: Growing need for nurses in dialysis, wound care, and occupational health.

Insider Tip: Attend the annual Rio Grande Valley Health Care Expo (usually in the fall in McAllen). It’s a massive event where all the major employers set up booths, and you can network directly with nurse managers and HR.

Getting Licensed in TX

If you’re from out of state, the Texas Board of Nursing (BON) process is straightforward but requires attention to detail. Texas is part of the Nurse Licensure Compact (NLC), so if your home state is a compact state (e.g., Florida, Oklahoma), you can practice here with your home license—but you must declare Texas as your primary state of residence. If not, you need a Texas single-state license.

Steps & Costs:

  1. NCLEX Examination: If you’re a new grad or need to take it, you must apply to the Texas BON for an authorization to test. The test fee is $200.
  2. License by Endorsement (Out-of-State Nurses):
    • Fee: $100 for the license application.
    • Fingerprinting: $38.25 (for background check).
    • Verification: You’ll need to verify your original license (usually from your home state’s BON). Some states charge a fee for this (e.g., $50-$100).
    • Transcripts: Your nursing school must send official transcripts directly to the Texas BON.
  3. Timeline: The entire process can take 6-12 weeks from the time you submit a complete application. Start early! Many employers will hire you pending licensure, but you must have a clear timeline.

Key Texas-Specific Rule: Texas has a strict "no re-entry" policy for expired licenses. If your license has been expired for more than 30 days, you must apply for a new license by examination (retaking the NCLEX). Do not let your license lapse.

Insider Tip: The Texas BON website is your best friend. Bookmark the "Licensure by Endorsement" page. Join the "Texas Nurses" Facebook group—nurses there share real-time updates on processing times and common application errors.

Best Neighborhoods for Registered Nurses

Where you live will define your commute, lifestyle, and budget. Mission is divided by the Expressway 83, with distinct character on each side.

Neighborhood Vibe & Commute Avg. 1BR Rent Best For
Mission Hills Upscale, quiet, golf courses. 10-15 min to MRMC. Safe, family-oriented. $850 - $1,100 Established professionals, families. Lower crime rates.
North Mission / Sharyland More residential, established homes. 10-15 min to most hospitals. Good schools. $750 - $950 Nurses looking to buy a first home. Strong community feel.
South Mission Closer to downtown, older homes, more diverse. 5-10 min to MRMC. $650 - $800 Budget-conscious nurses, those who prefer a shorter commute.
La Joya Southwest, more suburban, growing rapidly. 15-20 min commute. $700 - $900 Newer construction, families, easy access to the interstate.
McAllen (Near DHR/STHS) Urban, walkable, more nightlife. 15-20 min to Mission hospitals. $900 - $1,200 Nurses who want city amenities and are open to a longer commute.

Insider Tip: Traffic on Expressway 83 and 10th Street (the main drag) is predictable but can be heavy during shift changes (7 AM, 3 PM, 11 PM). Living on the same side of the expressway as your hospital can shave 10-15 minutes off your commute.

The Long Game: Career Growth

Mission is a great place to build a career, but you need to be strategic. The 6% 10-year job growth is steady, but the real advancement comes from specialization and leadership.

  • Specialty Premiums: The highest-paying specialties are Critical Care (ICU, CVICU), Emergency Department (TNCC certification helps), and Labor & Delivery. Nurses with these specializations can earn $5-$10/hour more than the median. Obtaining certifications like CCRN (Critical Care) or CEN (Emergency) is a direct path to higher pay.
  • Advancement Paths:
    • Clinical Ladder: Most hospitals have a clinical ladder program (e.g., RN I, II, III, IV). Moving up requires additional certifications, education, and committee work.
    • Leadership: Charge Nurse, Nurse Manager, Director. These roles often require a BSN (and sometimes a MSN) and pay a significant premium.
    • Advanced Practice: The University of Texas Rio Grande Valley has a strong Nurse Practitioner (NP) and Doctor of Nursing Practice (DNP) program. Many local nurses advance to NP roles, especially in family medicine, cardiology, or psychiatry, where demand is very high.
  • 10-Year Outlook: The demand will remain strong, driven by the region's population growth and the expansion of specialty services (e.g., more cardiac and stroke centers). Nurses with a BSN, specialty certifications, and flexibility (willingness to work nights/weekends) will have the most options and highest earning potential. Telehealth and remote care are also emerging as growth areas in the region.

Insider Tip: Join a hospital committee (e.g., Quality Improvement, Education). It’s a visible way to show leadership potential and is often a prerequisite for promotion to charge nurse or manager.

The Verdict: Is Mission Right for You?

Mission offers a compelling value proposition for nurses who prioritize financial stability, a lower cost of living, and a strong sense of community. It’s not a bustling metropolis, but it’s a growing hub with all the essential healthcare infrastructure.

Pros Cons
Excellent purchasing power with a median salary of $82,351 and a COL index of 85.6. Limited specialty options compared to major metros (e.g., fewer pediatric or oncology units).
Stable, growing job market with 785 positions and 6% projected growth. Car dependency is absolute; public transit is minimal.
Short, predictable commutes (5-20 minutes to most hospitals). Cultural/amenity gap if you’re used to major city arts, dining, and nightlife.
Strong community feel in neighborhoods like Mission Hills and Sharyland. Summer heat and humidity can be intense (May-September).
Pathway to homeownership is very realistic on a nurse's salary. Professional networking is more localized; you’ll need to build your network within the RGV.

Final Recommendation: Mission is an outstanding choice for:

  • New Graduates seeking a low-stress, affordable place to start their career.
  • Mid-Career Nurses looking to buy a home, start a family, and build long-term financial security.
  • Travel Nurses who want a stable, low-cost base between contracts.

It may be less ideal for:

  • Nurses seeking hyper-super-specialized roles (e.g., ECMO, pediatric heart surgery).
  • Those who thrive on the energy and anonymity of a large city.

FAQs

Q: Is the job market competitive for new graduate nurses in Mission?
A: It’s moderately competitive. Major hospitals like MRMC and DHR run residency programs for new grads, but spots are limited. Having a BSN, a good GPA, and being willing to work nights/weekends significantly increases your chances. Smaller clinics and home health agencies are often more accessible for first-time nurses.

Q: What is the typical nurse-to-patient ratio?
A: In Texas, there are no state-mandated ratios. It varies by unit and hospital. In Mission, Med-Surg ratios are typically 1:5-6, ICU is 1:2, and Telemetry is 1:4. Always ask about ratios during the interview process.

Q: Do I need a car in Mission?
A: Yes, 100%. There is no reliable public transportation system. A car is essential for getting to work, grocery shopping, and accessing amenities. The city is spread out, and walking is not practical for daily needs.

Q: What is the community like for nurses outside of work?
A: It’s very social and tight-knit. Many nurses socialize together, especially in the larger hospital systems. There are also active community groups, church groups, and outdoor activities (birding, hiking at Bentsen-RGV State Park) that are popular with healthcare professionals.

Q: How does the pay compare to the cost of living for a travel nurse?
A: Mission is a popular destination for travel nurses due to its

Data Sources: Bureau of Labor Statistics (OEWS May 2024), TX State Board, Bureau of Economic Analysis (RPP 2024), Redfin Market Data
Last updated: January 27, 2026 | Data refresh frequency: Monthly