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Registered Nurse in Odessa, TX

Comprehensive guide to registered nurse salaries in Odessa, TX. Odessa registered nurses earn $84,030 median. Compare to national average, see take-home pay, top employers, and best neighborhoods.

Median Salary

$84,030

Vs National Avg

Hourly Wage

$40.4

Dollars / Hr

Workforce

1.1k

Total Jobs

Growth

+6%

10-Year Outlook

The Registered Nurse's Guide to Odessa, TX

As a career analyst who’s spent years tracking the healthcare job market here in West Texas, I can tell you that Odessa is a unique beast. This isn't Austin or Dallas. It’s the heart of the Permian Basin, an energy town that’s always hungry for skilled medical professionals. The economy is tied to the price of oil, which means when the rigs are busy, the population swells, and the need for nurses intensifies. If you’re a Registered Nurse (RN) looking for a stable career with a lower cost of living and a grit-to-reward ratio that’s hard to beat, Odessa deserves your serious attention. This guide is your data-driven roadmap.

The Salary Picture: Where Odessa Stands

Let’s get straight to the numbers that matter. According to the most recent data from the Bureau of Labor Statistics (BLS) and industry reports, the financial reality for an RN in Odessa is solid, especially when you factor in the local cost of living.

The median salary for an RN in Odessa is $84,030/year. This breaks down to an hourly rate of $40.4/hour. This is slightly below the national average of $86,070/year, but that figure is heavily skewed by high-cost coastal cities. The real story is in the purchasing power. With Odessa’s cost of living index at 92.1 (US avg = 100), your dollar stretches significantly further here. The metro area supports 1,094 RN jobs with a 10-year job growth projection of 6%, which is stable and confident, reflecting the consistent demand in our regional healthcare system.

Experience-Level Breakdown

While the median is a great benchmark, your earning potential will climb with experience. Here’s a realistic breakdown based on local job postings and market analysis:

Experience Level Estimated Annual Salary Key Responsibilities
Entry-Level (0-2 yrs) $72,000 - $78,000 Staff nurse on Med-Surg or Telemetry units. Focus on foundational skills and time management.
Mid-Career (3-7 yrs) $82,000 - $92,000 Specialized units (ER, ICU, L&D). Precepting new nurses, charge nurse duties.
Senior (8-15 yrs) $90,000 - $105,000+ Clinical nurse specialist, unit manager, or education roles. Deep expertise in a specialty.
Expert (15+ yrs) $95,000 - $110,000+ Nurse practitioner (with additional certs), administrative leadership, or high-demand niche fields.

Comparison to Other Texas Cities

How does Odessa stack up? It’s a game of trade-offs.

City Median RN Salary Cost of Living Index Key Takeaway
Odessa, TX $84,030 92.1 Best for maximizing savings and buying power.
Houston, TX $88,490 96.5 Higher salary but fierce competition and longer commutes.
San Antonio, TX $78,650 91.8 Slightly lower salary, similar cost of living. More tourism/hospitality.
Dallas-Fort Worth $88,930 101.7 Top-tier salaries, but cost of living is above national average. High-stress, fast-paced.
Midland, TX $85,200 94.3 Sister city to Odessa. Very similar market, slightly higher salary potential.

Insider Tip: If you’re a new grad, don’t be discouraged by the entry-level range. Hospitals like Medical City Odessa and Odessa Regional Medical Center often offer sign-on bonuses (sometimes $10,000-$15,000) for 2-3 year commitments, which can effectively boost your first-year earnings into the mid-80s.

📊 Compensation Analysis

Odessa $84,030
National Average $86,070

📈 Earning Potential

Entry Level $63,023 - $75,627
Mid Level $75,627 - $92,433
Senior Level $92,433 - $113,441
Expert Level $113,441 - $134,448

Wage War Room

Real purchasing power breakdown

Select a city above to see who really wins the salary war.

The Real Take-Home: After Taxes and Rent

Salary is just a number. Here’s what your monthly budget looks like on the median salary of $84,030/year.

  • Gross Monthly Pay: ~$7,002
  • Estimated Taxes (22% bracket + FICA): ~$1,540 (This is an estimate; consult a tax professional for your situation)
  • Estimated Net Monthly Pay: ~$5,462
  • Average 1BR Rent: $1,127/month

Monthly Budget Breakdown

Here’s a conservative, realistic monthly budget for a single RN living in Odessa:

Category Estimated Cost Notes
Housing (1BR Apt) $1,127 This is the city average. You can find cheaper in older areas or more expensive in newer complexes.
Utilities (Elec, Gas, Water, Internet) $250 Odessa’s climate means AC costs in summer.
Car Payment & Insurance $450 Commuting is a must in Odessa. Car insurance is higher in Texas.
Groceries $400 Prices are reasonable; stores like H-E-B and Market Street are staples.
Health Insurance $300 Varies greatly by employer. Many hospitals offer good plans.
Student Loans/Debt $300 Adjust based on your personal situation.
Miscellaneous (Dining, Entertainment, Savings) $2,635 This is your "freedom fund." After necessities, you have over $2,600 left for savings, travel, or a mortgage.

Can They Afford to Buy a Home?

Absolutely, and this is where Odessa shines. The median home price in Odessa is approximately $265,000. With the $2,635/month left in your budget after essentials, a mortgage on a $250,000 home (with 20% down) would be around $1,200-$1,300/month (including taxes/insurance). This is easily manageable. Many nurses in Odessa are homeowners by their second or third year in the city. The housing market is more affordable here than in any major Texas metro.

💰 Monthly Budget

$5,462
net/mo
Rent/Housing
$1,912
Groceries
$819
Transport
$655
Utilities
$437
Savings/Misc
$1,639

📋 Snapshot

$84,030
Median
$40.4/hr
Hourly
1,094
Jobs
+6%
Growth

Where the Jobs Are: Odessa's Major Employers

The healthcare landscape in Odessa is dominated by a few key players, each with its own culture and specialty focus.

  1. Medical City Odessa: The largest hospital in the city, part of HCA Healthcare. It’s a Level II Trauma Center, which means the ER and ICU are always busy. They have a strong focus on cardiac care and oncology. Hiring is constant, especially for experienced nurses in critical care. They often have a robust residency program for new grads.

  2. Odessa Regional Medical Center (ORMC): The other major player, owned by Lifepoint Health. ORMC is known for its orthopedic and stroke care (a certified Primary Stroke Center). The vibe here is often described as more community-focused than the corporate feel of Medical City. They frequently hire for Med-Surg, Telemetry, and L&D.

  3. Texas Tech Physicians of the Permian Basin: This is the academic medicine arm. If you’re interested in teaching, research, or working in a clinic setting (rather than the acute care hospital floor), this is your destination. They have clinics specializing in everything from family medicine to neurology. Jobs here are competitive and often require a BSN.

  4. Ector County Independent School District (ECISD): School nursing is a stable, M-F, 8-3 job. With over 30,000 students, ECISD employs a significant number of nurses. The pay is competitive with the district’s pay scale, and the benefits are excellent. It’s a great option for nurses with families or those seeking a different pace.

  5. Odessa Family Health Center / Community Health Centers: These federally qualified health centers provide primary care to underserved populations. Working here offers a different kind of challenge and reward—managing chronic conditions, preventive care, and community outreach. It’s a path for nurses passionate about public health.

  6. Permian Regional Medical Center (in nearby Andrews): A 15-minute drive south, this hospital often has openings and draws from the Odessa talent pool. It’s a critical access hospital, offering a close-knit team environment.

Hiring Trends: The Permian Basin is currently experiencing a period of economic stability tied to sustained oil production. This has led to steady population growth, which directly translates to consistent healthcare demand. There is a particular shortage of nurses in ICU, ER, and Labor & Delivery. New grads are welcome, but experienced nurses can command higher salaries and sign-on bonuses.

Getting Licensed in TX

If you’re moving from another state, the Texas Board of Nursing (BON) is the gatekeeper. The process is straightforward but requires attention to detail.

  1. Endorsement Application: You must apply for licensure by endorsement through the Texas BON website. You’ll need your original compact license or verification from your current state’s board.
  2. Background Check: A fingerprint-based criminal history check is mandatory. The cost is about $40. Do this promptly, as it can take time.
  3. Nursing Licensure Compact (NLC): Texas is a member of the NLC. If you hold a multi-state license from another compact state (like Oklahoma, New Mexico, or Kansas), you can practice in Texas without obtaining a new license, but you must update your primary state of residence to Texas. If you’re coming from a non-compact state (e.g., California, New York), you must complete the full endorsement process.
  4. Costs & Timeline: The endorsement fee is $100. Total state fees: ~$140. The entire process can take 4-8 weeks if all documents are in order. Start this process at least two months before your planned move.

Pro Tip: Many local hospitals will sponsor your relocation and help with the licensing process, especially if you have experience. Ask about this during interviews.

Best Neighborhoods for Registered Nurses

Odessa is a sprawling city. Choosing where to live depends on your commute tolerance and lifestyle.

Neighborhood Vibe & Commute Avg. 1BR Rent
North Odessa (near Eastridge) Quiet, family-oriented. Closer to the newer Medical City Odessa. A 10-15 minute commute to most hospitals. $1,050 - $1,200
Central Odessa (near the University) More lively, closer to Texas Tech, downtown restaurants, and older homes. Commute to hospitals is 10-20 minutes. $950 - $1,150
West Odessa (near I-20) More rural, larger lots, lower rents. Commute can be 20-30 minutes, but traffic is minimal. Popular with those who want space. $800 - $1,000
Southside (near ORMC) Convenient for ORMC staff. Mix of older and newer developments. Close to shopping centers. $1,000 - $1,250
Midland (Sister City) A 20-minute commute but offers a different city feel. Often has more upscale amenities and a slightly different job market. $1,100 - $1,300

Commute Reality: Traffic in Odessa is not like a big city. The worst congestion is on Highway 191 (JB Simmons) and Loop 338 during rush hour. A 20-minute commute is considered normal. Most nurses I know plan their schedules to avoid peak traffic.

The Long Game: Career Growth

Odessa offers a clear path for advancement, but it requires proactivity.

  • Specialty Premiums: Certifications are king. Earning your CCRN (Critical Care), CEN (Emergency), or OCN (Oncology) can add $2-$5/hour to your base pay. Hospitals here actively pay for and reward certification.
  • Advancement Paths: The most common path is from staff nurse to Charge Nurse (shift leader), then to Unit Manager or Director. Another lucrative path is becoming a Family Nurse Practitioner (FNP). Midland-Odessa has a growing demand for FNPs in primary care and urgent care, with salaries often exceeding $110,000/year. Texas Tech University Health Sciences Center has a well-regarded FNP program locally.
  • 10-Year Outlook (6% Growth): This growth is driven by an aging population and the expansion of specialty services. We're seeing more outpatient surgery centers, specialty clinics (e.g., orthopedic, cardiology, and pain management), and home health agencies. The energy industry’s volatility is a risk, but healthcare demand is generally recession-proof. The key is to build a broad skillset early on.

The Verdict: Is Odessa Right for You?

Odessa is a city of contrasts: it’s affordable yet offers competitive pay, it’s a blue-collar energy town with a growing healthcare sector, and it’s a place where you can build a comfortable life without the stress of a major metropolis.

Pros Cons
High Purchasing Power: Your salary goes much further here. Isolation: It’s a 4-5 hour drive to the nearest major city (El Paso, Lubbock, Dallas).
Strong Job Market for Nurses: Consistent demand, especially in critical care. Climate: Hot, dry summers and dusty, windy conditions year-round.
Short Commutes: Easy living without traffic nightmares. Cultural Amenities: Limited compared to larger cities (fewer museums, concert venues).
Sense of Community: You’ll know your colleagues and neighbors. Economic Ties to Oil: Job stability can be indirectly tied to oil prices.
Family-Friendly: Good schools, affordable homes, safe suburbs. Nightlife & Dining: It exists, but options are limited. You learn to love local spots.

Final Recommendation: Odessa is an excellent choice for RNs at all career stages, but it’s particularly ideal for mid-career nurses looking to buy a home and save aggressively, and for new grads who want hands-on experience in high-acuity settings without being lost in a sea of thousands of nurses. If you crave a fast-paced, 24/7 city with endless options, this isn’t it. But if you value financial stability, a strong work-life balance, and being part of a tight-knit medical community, Odessa is a smart, strategic move.

FAQs

Q: What’s the cost of living really like?
A: It’s very manageable. The Cost of Living Index of 92.1 means you’ll spend about 8% less than the national average. Groceries, utilities, and especially housing are where you’ll save the most. A night out is affordable, and property taxes, while high in Texas, are offset by no state income tax.

Q: Is it hard to find housing?
A: No. The rental and home markets are stable. While there’s competition for the best apartments, inventory is sufficient. The key is to start your search 30-60 days before your move. Use local realtors and apps like Zillow, but also drive around neighborhoods—some of the best rentals aren’t listed online.

Q: What’s the work culture like at the hospitals?
A: It’s a blend. Medical City Odessa can feel corporate and fast-paced, with more resources. ORMC often feels more like a community hospital where everyone knows each other. Both demand resilience and teamwork. The pace is intense due to the high acuity of patients (often related to the energy sector’s occupational hazards), but the camaraderie is strong.

Q: How do I stand out as an applicant?
A: Specialize. Get your ACLS, PALS, or CCRN. Highlight any experience in high-acuity units. For new grads, emphasize your clinical rotations in similar settings. Tailor your resume to the specific hospital’s focus (e.g., highlight cardiac skills for Medical City). Be prepared to interview quickly—hiring moves fast here.

Q: Is there anything to do outside of work?
A: Yes, but you have to know where to look. The Permian Basin Petroleum Museum is a unique local gem. There are great parks, hiking at Monahans Sandhills State Park (an hour away), and a surprisingly vibrant local music and food scene. The city also hosts the annual Sandhills Stock Show & Rodeo. For bigger events, most locals make the 4-hour drive to Dallas or Austin for a weekend.

Data Sources: Bureau of Labor Statistics (OEWS May 2024), TX State Board, Bureau of Economic Analysis (RPP 2024), Redfin Market Data
Last updated: January 27, 2026 | Data refresh frequency: Monthly